{"created":"2023-06-19T12:16:05.335746+00:00","id":323,"links":{},"metadata":{"_buckets":{"deposit":"c235b670-3e7e-41a7-a447-b4bb205b13d4"},"_deposit":{"created_by":24,"id":"323","owners":[24],"pid":{"revision_id":0,"type":"depid","value":"323"},"status":"published"},"_oai":{"id":"oai:hachinohe-hachitan.repo.nii.ac.jp:00000323","sets":["247:321"]},"author_link":["409"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"108","bibliographicPageStart":"91","bibliographicVolumeNumber":"42","bibliographic_titles":[{"bibliographic_title":"八戸学院短期大学研究紀要"}]}]},"item_10002_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"骨髄異形成症候群(MDS;myelodysplastic syndrome)はあまり馴染みのない疾患と思われがちであるが、実は高齢化に伴い増加しつつある病気である。原因不明の血球減少で発症するが、診断がつきにくく難渋することが多い。近年、MDSに対する新薬の出現に伴う薬物療法、支持療法、および造血幹細胞移植の適応拡大などにより、その治療成績が向上してきている。また、遺伝子解析の進歩によって、MDSに出現する遺伝子変異が多数報告されるようになり、病態、予後予測、および治療法などと関連する知見が積み重ねられつつある。ここ数年の間に明らかになった知見を含めてMDSの病態および治療の現状について述べる。","subitem_description_type":"Other"}]},"item_10002_select_24":{"attribute_name":"論文種別","attribute_value_mlt":[{"subitem_select_item":"総説"}]},"item_10002_select_25":{"attribute_name":"学部学科","attribute_value_mlt":[{"subitem_select_item":"看護学科"}]},"item_10002_select_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_select_item":"八戸学院短期大学"}]},"item_10002_select_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_select_item":"2187-8110"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高橋, 正知"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-04-04"}],"displaytype":"simple","filename":"総説  骨髄異形成症候群の病態と治療.pdf","filesize":[{"value":"2.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PDF(本文)","url":"https://hachinohe-hachitan.repo.nii.ac.jp/record/323/files/総説  骨髄異形成症候群の病態と治療.pdf"},"version_id":"976001f4-ad15-4007-96f3-c290f6eb36c8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"骨髄異形成症候群","subitem_subject_scheme":"Other"},{"subitem_subject":"病態","subitem_subject_scheme":"Other"},{"subitem_subject":"治療","subitem_subject_scheme":"Other"},{"subitem_subject":"myelodysplastic syndrome","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pathogenesis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"tretment","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"総説 : 骨髄異形成症候群の病態と治療","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"総説 : 骨髄異形成症候群の病態と治療"},{"subitem_title":"Review : Pathogenesis and treatment of myelodysplastic syndrome（MDS）","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"24","path":["321"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-04-04"},"publish_date":"2016-04-04","publish_status":"0","recid":"323","relation_version_is_last":true,"title":["総説 : 骨髄異形成症候群の病態と治療"],"weko_creator_id":"24","weko_shared_id":-1},"updated":"2023-06-19T12:41:17.934360+00:00"}